Understanding sickle cell

What sickle cell is, why it hits children in Uganda so hard, and how we help.

Sickle cell disease is an inherited condition of the blood. Healthy red blood cells are round and flexible, but in sickle cell they become stiff and curved, like a sickle. These cells get stuck in small blood vessels and block the flow of blood and oxygen.

The result is sudden attacks of severe pain, known as crises, along with anaemia, tiredness and a much higher risk of serious infections. Without regular care, sickle cell can be life threatening, especially for young children.

Why it matters in Uganda

Sickle cell is common in Uganda. Studies estimate that around one in eight Ugandans carries the sickle cell trait, and thousands of babies are born with the disease every year. Many families cannot afford the daily medicine, good food and quick hospital care that keep a child well. Children with sickle cell can also face fear and stigma from people who do not understand the condition.

How we help

We stand with children living with sickle cell and their families. That means daily medication such as folic acid and pain relief, nutritious food, transport to hospital during a crisis, help with clinic costs, and home visits and prayer for parents who are carrying a heavy load.

World Sickle Cell Day falls on 19 June each year, but children with sickle cell need support every day. A gift to our sickle cell support helps keep that care going.

Back to all stories